![]() The diagnosis is mainly clinical, based on the history and physical findings. 3, 18– 21 Moisture, maceration, trauma, and epithelial defects in the penile area are other predisposing factors. 12, 16, 17 The disease is more common in individuals with the following factors: immunodeficiency, unprotected sexual intercourse, multiple sexual partners, sexual partner with multiple sexual partners, prior sexually transmitted disease, sexual intercourse at an early age, shorter time interval between meeting with a new partner and engaging in sexual activity, non-circumcision, and smoking. 13 The incubation period for genital infection varies from 3 weeks to 8 months, with an average of 2–4 months. 1, 15 The HPV virus invades cells in the basal layer of the epidermis through micro-abrasions in the skin or mucosa. 8 In children, HPV infection may result from sexual abuse, vertical transmission, autoinoculation, hetero-inoculation (nonsexual contact with a caregiver), and transmission via fomites. 8 In adults, genital HPV infection is predominately transmitted by sexual intercourse and, less commonly, by oral sex, skin-to-skin transmission, and fomites. 14 It is possible to be infected with different HPV types at the same time. Approximately 90% of genital warts are caused by the low-risk types HPV-6 and/or HPV-11. 4, 11, 12 HPV can be divided into high-risk or low-risk types based on their risk for cancer. 4, 11, 12 More than 40 HPV types can be transmitted sexually. More than 200 HPV types have been isolated thus far, of which more than 100 HPV genotypes have been sequenced. 11 The virus-like particle containing L1 is used in the manufacturing of HPV vaccines. 11 The virus has an eight kilobase circular genome that encodes eight genes, including the genes for the two encapsulating structural proteins, namely L1 and L2. HPV is a nonenveloped, capsid, double-stranded deoxyribonucleic acid (DNA) virus belonging to the Papillomavirus genus of the Papillomaviridae family and infects only humans. Second-line therapies include topical/intralesional/intravenous cidofovir, topical 5-fluorouracil, and topical ingenol mebutate. Patients who do not respond to first-line treatments may respond to other therapies or a combination of treatment modalities. Clinician-administered therapies include podophyllin, cryotherapy, bichloroacetic or trichloroacetic acid, oral cimetidine, surgical excision, electrocautery, and carbon dioxide laser therapy. Patient-administered therapies include podofilox (0.5%) solution or gel, imiquimod 3.75 or 5% cream, and sinecatechins (polypheron E) 15% ointment. Active treatment is preferable to watchful observation to speed up clearance of the lesions and to assuage fears of transmission and autoinoculation. Approximately one-third of penile warts regress without treatment and the average duration prior to resolution is approximately 9 months. Lesions may be filiform, exophytic, papillomatous, verrucous, hyperkeratotic, cerebriform, fungating, or cauliflower-like. Penile warts typically present as asymptomatic papules or plaques. So if you notice a wart, it’s best to get tested and treated to help lower the risk of passing genital warts on to a partner.Penile warts are caused by human papillomavirus (HPV), notably HPV-6 and HPV-11. ![]() ![]() You’re more likely to pass genital warts when you’re having symptoms. So you can’t get genital warts by touching yourself (or a partner) with a wart that’s on your hand or foot. Genital warts are different from warts you might get elsewhere on your body. You can also pass genital warts to a baby during vaginal childbirth, but that’s pretty rare. You can spread them even when you don’t have any visible warts or other symptoms, though that’s less common. Genital warts can be spread even if no one cums, and a penis doesn’t have to go inside a vagina or anus to get them. You get genital warts from having skin-to-skin contact with someone who’s infected, often during vaginal, anal, and oral sex. Genital warts are common - about 360,000 people get them each year. Other “low-risk” types of HPV can cause warts on your vulva, vagina, cervix, rectum, anus, penis or scrotum. Sometimes certain types of “high-risk” HPV can develop into cancer if left untreated. It’s the most common STD, but most of the time it goes away on its own. You might’ve heard that some types of HPV can cause cancer, but they’re NOT the same kinds that give you genital warts. They’re caused by certain types of human papillomavirus ( HPV). Genital warts show up on the skin around your genitals and anus. Find Abortion Provider Genital warts are caused by HPV
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